Clotri-Denk 1% is primarily used to treat fungal infections of the skin and body such as athlete’s foot, fungal nail infections, ringworm and vaginal candidiasis. It works by destroying the fungus that causes the infection.The cream should be applied thinly and evenly to the affected area 2-3 times daily and rubbed in gently with a cotton swab or gauze pad. Clotri-Denk 1% cream should be used for skin only and if it accidentally gets into your eyes, mouth or nose, rinse with water. Do not apply more than the recommended dosage to avoid unpleasant side effects.